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Indianapolis at Cincinnati – 7:00 ET
- Over is 5-0 in the last 5 meetings in Cincinnati.
- Favorite is 4-1 ATS in their last 5 meetings.
- Home team is 4-1 ATS in their last 5 meetings.
Pick: Bengals -2.5
Miami at Atlanta – 7:00 ET
- Under is 4-1 in the last 5 meetings.
- Favorite is 4-1-1 ATS in their last 6 meetings.
Pick: Dolphins -1
NY Jets at Philadelphia – 7:00 ET
- Jets are 0-4 ATS in their last 4 meetings.
Pick: Jets -4
Cleveland at Detroit – 7:00 ET
- Over is 5-1 in the last 6 meetings.
Pick: Browns -2.5
New England at NY Giants – 7:00 ET
- Underdog is 5-0 ATS in their last 5 meetings.
- Under is 5-2 in the last 7 meetings.
- Patriots are 0-5 ATS in their last 5 meetings.
Pick: Giants -2.5
Washington at Baltimore – 7:30 ET
- Under is 5-1 in the last 6 meetings.
- Favorite is 4-1 ATS in their last 5 meetings.
Pick: Redskins +6.5
Carolina at Pittsburgh – 7:30 ET
- Over is 4-1 in the last 5 meetings.
- Panthers are 0-6 ATS in their last 6 meetings.
Pick: Steelers -2.5
Jacksonville at Tampa Bay – 7:30 ET
- Underdog is 5-1 ATS in their last 6 meetings.
- Over is 4-1 in the last 5 meetings.
Pick: Bucs -1.5
Buffalo at Chicago – 8:00 ET
- Under is 4-1 in the last 5 meetings.
- Home team is 3-1-1 ATS in their last 5 meetings.
Pick: Bills +3
Minnesota at Tennessee – 8:00 ET
- Favorite is 4-0 ATS in their last 4 meetings.
- Vikings are 5-1 ATS in their last 6 meetings.
- Home team is 4-1 ATS in their last 5 meetings.
Pick: Titans -1
LA Rams at New Orleans – 8:00 ET
- Home team is 6-0 ATS in their last 6 meetings.
- Over is 4-1 in the last 5 meetings in New Orleans.
- Rams are 6-2 ATS in their last 8 meetings.
Pick: Saints -4
Dallas at Houston – 8:00 ET
- Under is 4-0 in the last 4 meetings.
Pick: Texans -4
Green Bay at Kansas City – 8:30 ET
- Over is 4-1 in the last 5 meetings.
- Underdog is 4-1 ATS in their last 5 meetings.
Pick: Chiefs -3.5
Denver at Arizona – 10:00 ET
- Over is 4-1 in the last 5 meetings.
- Underdog is 4-1 ATS in their last 5 meetings.
Pick: Cardinals -3
LA Chargers at San Francisco – 10:00 ET
- Chargers are 4-1 ATS in their last 5 meetings.
- Road team is 4-1 ATS in their last 5 meetings.
Pick: Chargers +3.5
Oakland at Seattle – 10:00 ET
- Over is 8-1 in the last 9 meetings in Seattle.
- Home team is 8-1 ATS in their last 9 meetings.
- Raiders are 9-3 ATS in their last 12 meetings.
- Over is 13-5 in the last 18 meetings.
Pick: Seahawks -3
